Sugammadex by ideal body weight versus 20% and 40% corrected weight in bariatric surgery – double-blind randomized clinical trial
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چکیده
منابع مشابه
[Sugammadex by ideal body weight versus 20% and 40% corrected weight in bariatric surgery - double-blind randomized clinical trial].
BACKGROUND AND OBJECTIVES The weight parameters for use of sugammadex in morbidly obese patients still need to be defined. METHODS A prospective clinical trial was conducted with sixty participants with body mass index≥40kg·m-2 during bariatric surgery, randomized into three groups: ideal weight (IW), 20% corrected body weight (CW20) and 40% corrected body weight (CW40). All patients received...
متن کاملSugammadex and Ideal Body Weight in Bariatric Surgery
Background. The obese patients have differences in body composition, drug distribution, and metabolism. Sugammadex at T 2 recovery in a dose of 2 mg kg(-1) of real body weight (RBW) can completely reverse the NMB block; in our study we investigated the safety and efficacy of Sugammadex dose based on their ideal body weight (IBW). Methods. 40 patients of both sexes undergoing laparoscopic bariat...
متن کاملSugammadex ideal body weight dose adjusted by level of neuromuscular blockade in laparoscopic bariatric surgery.
BACKGROUND Bariatric surgery patients are at risk of perioperative airway collapse. Neuromuscular blockade should be fully reversed before tracheal extubation. The optimal dosage of the reversal agent sugammadex in the morbidly obese is still unknown. This study explored the sugammadex dose adjusted according to train-of-four ratio (TOFR). METHODS Prospective observational study of consecutiv...
متن کاملSugammadex and Ideal Body Weight in Bariatric Surgery: The Debate Continues
I read with great interest the paper by Sanfilippo et al., evaluating the safety and efficacy of sugammadex administered on the basis of ideal body weight (IBW) to reverse neuromuscular blockade (NMB) at the reappearance of second twitch during train-of-four (TOF) stimulation [1]. However, this study raises several issues that deserve comment. First, the authors chose a TOF ratio of 0.9 after s...
متن کاملIdeal versus corrected body weight for dosage of sugammadex in morbidly obese patients.
To date, the dosing of sugammadex is based on real body weight without taking fat content into account. We compared the reversal of profound rocuronium-induced neuromuscular blockade in morbidly obese patients using doses of sugammadex based on four different weight corrections. One hundred morbidly obese patients, scheduled for laparoscopic bariatric surgery under propofol-sufentanil anaesthes...
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ژورنال
عنوان ژورنال: Brazilian Journal of Anesthesiology (English Edition)
سال: 2018
ISSN: 0104-0014
DOI: 10.1016/j.bjane.2017.10.011